Urologie pro praxi 2/2002
Kombinační medikamentózní léčba BPH – ano či ne?
Drug Combination in the of treatment of BPH – Yes or No? Advances in our understanding of the natural course of benign prostatic hyperplasia have generated an escalation of drug use over other treatment modalities. There are two major groups of drugs: alfa-1 blockers and 5-alfa reductase inhibitors. The efficacy and safety of both groups have been proved in numerous randomized double blinded, placebo controlled studies. Recently in the literature we found the first information of drug combination in the treatment of BPH. The concept warranting its use is derived from the different mechanism of action of both drug groups. Whether patients would benefit from a permanent or temporary combination therapy still remains the unanswered question. Key words: finasteride, doxazosin, terazosin, BPH.
