Urologie pro praxi 2/2026
Drug-induced urolithiasis
Although drug-induced urolithiasis does not occur very frequently, it is by no means rare. It is reported to account for 1–2 % of cases of urolithiasis. This type of lithiasis should be taken into consideration in patients taking a medication from the group of potentially lithogenic drugs as well as in those who have recurrent lithiasis and are suspected to have a lithiatic-metabolic disorder. The article lists the most high-risk medications identified to date that can cause iatrogenic lithiasis, particularly when patients take these medications in the long-term and/or in higher doses.
Keywords: iatrogenic urolithiasis, diuresis, urine pH, crystallization inhibitors.