Urologie pro praxi 5/2001
Benigní hyperplázie prostaty a terapie alfablokátory
Benign Prostatic Hyperplasia (BPH) and Therapy with Alfa-blockers Hyperplasia of the prostate (benign enlargement of the gland) is a common disease and it’s clinical course depends on the age. Histological ch anges can be detected in men from the age of 40 and above, but sometimes even earlier. These changes are not usually accompanied by any symptoms. In men in their fifties, signs of obstruction of micturition, due to a changed prostatic gland, are easily found and hyperplasia is present in virtually all the histologic specimens. About half of the men over 60 years of age suffer from difficulties in micturition, and half of those affected seek medical advice. After proper diagnostic evaluation, these patients may then be suitable candidates for initiation into one of the treatment modalities. In BPH management the most common pharmacotherapy used is the use of alfa-blockers and the reason for this is outlined in this article. Key words: BPH, pharmacotherapy, alfa-blockers.
