Psychiatria pre prax 3/2025
Treatment of pharmacoresistant states in psychiatry – Part 1: Treatment-resistant schizophrenia
The paper is focused on pharmacotherapy of treatment-resistant schizophrenia and exclusion of pseudoresistance. The treatment options including switch, augmentation and combination of antipsychotics are described. Finally, perspective substances are briefly mentioned.
Keywords: treatment-resistant schizophrenia, pseudoresistance, switch of antipsychotics, clozapine, augmentation, combination of antipsychotics, precision psychiatry