Základy manažmentu niektorých nežiaducich účinkov liečby inhibítormi imunitných kontrolných bodov – 1. časť // SOLEN

Onkológia 4/2025

The basics of management of certain adverse events of immune checkpoint inhibitors

This review is devoted to the basics of management of certain immune-related adverse events related to therapy with immune checkpoint inhibitors. Generally, their incidence is higher in immunotherapy combination compared to mono-immunotherapy. This paper introduces the analysis on the diagnosis and therapy of immune-related endocrinopathies (hypothyroidism and thyrotoxicosis), diabetes mellitus, skin rash, pneumonitis, hepatitis, and colitis.

Keywords: immunotherapy, immune checkpoints, immune-related adverse events, management, immunosuppressive therapy