Onkológia 2/2025
Radiotherapy in treatment of cervical carcinoma
Cervical cancer is the second most common cancer in women under the age of 45 and the third most common cause of death in women. In Slovakia alone, approximately 600 new cases and 200 women die from cervical cancer every year. The main cause of cervical cancer is a long-term infection with HPV (human papillomavirus). Treatment of early stages FIGO IA, , IB1, IB2, IIA1 is surgical. For early tumors over 4 cm (FIGO IB3 a IIA2) and locally advanced diseases FIGO (IIB – IVA), radical chemoradiotherapy remains standard treatment. In metastatic stages, systematic treatment is primarily useda combination of chemotherapy and biological treatment, to wich immunotherapy is added. Immunotherapy significantly changes treatment procedures and we can expect that in the near future it will be used more and more in cervical cancer, and not only in metastatic disease.
Keywords: cervical carcinoma, surgery, radiotherapy, brachytherapy, chemotherapy