Onkológia 4/2026

Summary

The administration of systemic anticancer therapy is a time- and resource-intensive process for both patients and healthcare professionals. Prolonged time spent in ambulatory treatment units increases service burden and contributes to so-called time toxicity. The aim of this article is to highlight practical strategies that may safely reduce patient chair time without compromising treatment quality or safety. The main approaches include switching selected supportive medications from intravenous to oral administration, using drug compatibility and Y-site compatibility, shortening infusion duration, replacing intravenous treatment with subcutaneous formulations, and extending dosing intervals for selected agents. These interventions may reduce administration time, decrease the number of intravenous manipulations, and improve ambulatory treatment capacity. However, their use must be individualized and based on available evidence, product information, and local standard practices.

Keywords: systemic anticancer therapy, chair time, time toxicity, intravenous administration, subcutaneous administration, premedication