Terapie třesu // SOLEN

Neurológia pre prax 4/2025

Therapy of tremor

Tremor is the most common type of movement disorder, and its precise syndromological classification is essential for effective therapy. This review summarizes current treatment options for the major clinical tremor syndromes, particularly essential tremor, Parkinsonian tremor, dystonic tremor, and functional tremor, as well as less frequent causes including Wilson’s disease and multiple sclerosis. Special attention is given to symptomatic pharmacotherapy, with propranolol and primidone remaining the mainstays of treatment for essential tremor, including considerations of dosage, efficacy, and potential risks. The article also discusses alternative pharmacological options, neurosurgical approaches including deep brain stimulation and newer lesion-based techniques, and non-pharmacological strategies in functional tremor. Diagnostic challenges in mixed tremor syndromes are addressed, and the importance of an individualized treatment approach is emphasized.

Keywords: tremor, essential tremor, Parkinson’s disease, dystonic tremor, deep brain stimulation, tremor pharmacotherapy