Neurológia pre prax 3/2025
How the patient and her neurologists managet to win the fight against the chronic form of cluster headache – a case report
This case report describes a rare disease – the chronic form of cluster headache. Here a female patient with this severe neurological disorder is discussed. The difficulties in understanding the pathogenesis of cluster headache in general are noted. Our patient tried different types of “classical” treatment but none of those led to a sufficient effect and her quality of life was very low for a long period of time. Lithium therapy also did not help. Later, galcanezumab was prescribed in our outpatient clinic, which led to a significant decrease in headache frequency and headache intensity. Our patient also suffered from symptoms of depression, which significantly improved at the time when the cluster headache manifestations improved. Thus, at some point, she returned to her full-time job after a very long period of disability. There are different publications which show the positive effect of galcanezumab in patients with cluster headaches. However, most of the studies were conducted on people with the episodic form. In this text concrete scientific data from different studies about galcanezumab with this indication are also discussed.
Keywords: cluster headache treatment, chronic form, galcanezumab, quality of life, lithium in cluster headache
