Neurológia pre prax 3/2026

Pain as one of the symptoms of multiple sclerosis

Pain is a common, but often underestimated symptom of multiple sclerosis (MS). It significantly affects the patient’s quality of life, working capacity as well as their mental state. The most common type is neuropathic pain, followed by pain associated with spasticity and nociceptive musculoskeletal pain; moreover, patients with MS tend to develop headaches more frequently. Diagnosing the type of pain and choosing the appropriate treatment are often challenging and require a multidisciplinary approach. The article presents an overview of the pathophysiology, clinical forms, diagnostic options, and current therapeutic approaches to pain management in patients with MS in routine clinical practice.

Keywords: pain, multiple sclerosis, neuropathic pain, spastic pain