Amyotrofická laterální skleróza: aktuální doporučení k diagnostice a terapii // SOLEN

Neurológia pre prax 3/2025

Amyotrophic lateral sclerosis: new guidelines on diagnostics and management

Amyotrophic lateral sclerosis (ALS) is a fatal, rapidly progressive neurodegenerative disease that primarily affects motor neurons in the brain and/or spinal cord. In recent years, a number of new recommendations have been published regarding the diagnosis of ALS, including the approach to genetic testing of these patients, as well as the therapy or general comprehensive management of this disease and its complications and comorbidities. The aim of this article is to summarize these recommendations and the most important current knowledge about this very serious disease.

Keywords: amyotrophic lateral sclerosis, motor neuron disease, genetic testing, frontotemporal dementia, electromyography, gastrostomy, noninvasive ventilation, living will