Hypolipidemika a cílové hodnoty lipidů // SOLEN

Via practica 1/2019

Hypolipidemic treatment and target values of lipids

Hypolipidemics are one ofthe mostfrequently prescribed drugs in theworld. Last year, the updated guidelines were released: European Guidelines on cardiovascular disease prevention in clinical practice by European Society of Cardiology (ESC) and ESC/EAS (European Atherosclerosis Society) Guidelines forthe Management of Dyslipidaemias. Both ofthem contain changes mainly in estimation ofindividual cardiovascularrisk and target levels of LDL-cholesterol. Targeting these goals is usually very difficult and often impossible in patients with familial hypercholesterolemia. PCSK9 inhibitors are a new and very potent hypolipidemics that should make target LDL-cholesterol levels reachable.

Keywords: dyslipidemia, cardiovascular diseases, LDL cholesterol, triglycerides, statins, PCSK9 inhibitors