Vaskulárna medicína 1/2018
Periférne artériové ochorenie dolných končatín a globálne kardiovaskulárne riziko – možnosti ovplyvnenia v klinickej praxi
Peripheral arterial disease of lower extremity and global cardiovascular risk
Effective cardiovascular risk treatment is underestimated in clinical practice despite significantly increased cardio-cerebro-vascular mortality and morbidity in Peripheral Arterial Disease of Lower Extremity (PAD) patients. Smoking cessation, longlasting good metabolic diabetes mellitus control, effective blood pressure control, healthy lifestyle and physical activity are important tools in conservative treatment. PAD patients have very high CV risk and the goal level of LDL cholesterol is less than 1,8 mmol/l or even lower according to new studies. What cannot be forgotten is modification of life-style especially in reduction of remnant lipoproteins, which play an important role in peripheral circulation. ACE-inhibitors, statins, antiplatelet therapy with preference of clopidogrel in symptomatic PAD patients are essential for global CV risk control according last ESC/ESVS guidelines.
Keywords: arterial hypertension, risk factors, cardiovascular risk, peripheral arterial disease of lower extremity
