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Psychiatria pre prax 6/2006
THE INTRODUCTION TO THE BIOLOGICAL TREATMENT OF RESISTANT DEPRESSION
Depressive disorder is relatively common disease in population. Lifetime prevalence of major depression is 5–12% in men and 9–26% in women. Approximately 30% of patients treated with first antidepressants achieve remission. The resistant depression is commonly defined as depression which was unsuccessfully treated by 2 antidepressants from various groups. The authors comment possibilities of resistant depression treatment (change of antidepressants, augmentation and combination of antidepressants, repetitive transcranial magnetic stimulation, electroconvulsive therapy etc.).
Keywords: resistant depressive disorder, definition, treatment.
