Psychiatria pre prax 4/2018
Liečba rezistentnej schizofrénie kombináciou klozapínu a depotného aripiprazolu
We present a case report of a 34-year-old female patient treated for schizophrenia since 18 years of age, who has been hospitalized 20 times in various psychiatric facilities for relapse of the disease, also due to insufficient outpatient compliance. She has a history of several serious suicide attempts. A wide variety of first and second generation antipsychotics, including long-acting injections (LAI) and electroconvulsive treatment, have been used in her treatment. However, it was not possible to keep the patient in remission. Especially in recent years, the patient has significantly gained weight. She was hospitalized at our department in 2016 for relapse despite of clozapine treatment. The combined treatment with LAI aripiprazole and clozapine provided the patient with the longest remission in the course of the disease.
Keywords: treatment-resistant schizophrenia, adherence, clozapine, LAI aripiprazole, remission












