Onkológia 1/2009

Primary breast lymphoma – rewiev and case reports

Primary breast lymphoma (PBL) is a rare lymphoproliferative disease. More than 80 % cases show B-cell origin. Diffuse large B-cell lymphoma is most common type. The treatment depends on the histologic type of the non-Hodgkin lymphoma. Mastectomy and axillary dissection are poor factor for overall survival and lymphoma specific survival according to the retrospective analyses and therefore surgery should be limited to the biopsy. Cases demonstrate different histologic types of the PBL with different surgery and chemotherapy approach.

Keywords: primary breast lymphoma, extra-nodal non-Hodgkin lymphoma, diffuse large B cell lymphoma, mastectomy and axillary dissection