Klinická skúsenosť s liečbou mnohopočetného myelómu monoklonálnou protilátkou v monoterapii – kazuistika // SOLEN

Onkológia 4/2018

Klinická skúsenosť s liečbou mnohopočetného myelómu monoklonálnou protilátkou v monoterapii – kazuistika

Clinical experience of multiple myeloma therapy by monoclonal antibody in monotherapy – case report

Purpose: Over the last decade, significant progress has been made in recognizing multiple myeloma biology and individualized treatment. Several drug groups have been put into practice, such as proteasome inhibitors, immunomodulators and from 2015 first monoclonal antibody, that have prolonged treatment responses. Case: In our work we present the case of a patient with multiple myeloma whose treatment with daratumumab led to a long-term control of a resistant / relapsing disease in a very complicated course of the disease. Conclusion: The treatment results of the reported patient show the importance of using the daratumumab therapy to achieve prolongation of progression free survival.

Keywords: multiple myeloma, daratumumab, progression free survival