Neurológia pre prax 3/2018
Periferní neuropatie u dětí
Peripheral neuropathy in children Most peripheral nerve disorders have a gradual and slow progressive course. But an acute onset may occur with autoimmune and infectious inflammation, metabolic disorders or intoxication. Many systemic diseases, as well as drugs, also affect the peripheral nervous system. Peripheral neuropathy typically develops with symmetrical and predominantly distal affections. The combination of sensory and motor lesions is the most common, but in some cases motor or sensory abnormalities can predominate, and autonomic symptoms may also occur. Examination of peripheral nerve disorder involves a careful history, including a family history. It is followed by neurological, electrophysiological and biochemical, serological, immunological, cerebrospinal fluid or genetic tests; or imaging. The most common polyneuropathy in childhood is hereditary motor and sensory neuropathy.
Keywords: peripheral neuropathy, diagnostics, electromyography, axonal and demyelinating lesion, acquired neuropathies, hereditary neuropathy, neuropathies associated with hereditary disorders
