Kortikálny zápal v patogenéze sclerosis multiplex // SOLEN

Neurológia pre prax 4/2019

Cortical inflammation in pathogenesis of multiple sclerosis

Multiple sclerosis is an autoimmune-related disease characterized by inflammation and neurodegeneration. Looking at inflammation, its characteristics, intensity and localization has undergone changes in recent years. Acute and chronic inflammation is present in all forms of SM. Cortical demyelination is an important pathological substrate for irreversible functional disability, progression and cognitive impairment. A comprehensive understanding of inflammatory manifestations can help us to set up individualized therapy for the patient.

Keywords: multiple sclerosis, acute and chronic inflammation, cortical demyelination