Neurológia pre prax 4/2017

Functional basal ganglia interconnection

The circuits of basal ganglia support a wide range of sensorimotor, cognitive and emotional- motivational brain functions. A main role of the basal ganglia is a learning and selection of the most appropriate motor and behavioral programs. The internal functional organization of the basal ganglia is important for selection mechanisms. Development of basal ganglia and cerebellum takes place over an extended period of time, in human spanning almost two decades. Factor that affect the normal development of the brain affect the functions of both structures. An important issue for future research might be the more precise determination of the contribution of the basal ganglia and the cerebellum to the learning of skillful movements, an interesting question is the extent of interaction between these two structures.

Keywords: cerebellum, dopamine, development, circuit, organization, cortex