Neurológia pre prax 5/2025
Diagnosis and scales in myasthenia gravis: development and current use in clinical practice
Myasthenia gravis is a chronic autoimmune disorder affecting neuromuscular transmission, leading to increased muscle fatigability and weakness. In recent years, treatment options have expanded significantly, increasing the need for standardized patient monitoring. The range of available objective assessments and patient-reported outcome measures is quite wide. However, in clinical practice and research, the following four basic ones are recommended: MGFA classification, QMG score, and subjective tools such as MG-ADL and MG-QoL-15r. The key is the assessment of the treatment response by the patient himself, which is why the PASS is considered as the fifth tool. The combination of subjective and objective methods allows for effective disease monitoring and optimization of therapy.
Keywords: myasthenia gravis, bedside tests, MGFA, MG-ADL, QMGS, quality of life
