Anti-NMDA encefalitida? Ne. Falešná pozitivita anti-NMDA protilátek u pacienta s Creutzfeldt-Jakobovou nemocí // SOLEN

Neurológia pre prax 1/2020

Autoimmune encephalitis? Not. False positivity of anti-NMDA antibodies in patient with Creutzfeldt-Jacob disease

Anti-NMDA encephalitis is one of many types of autoimunne encephalitis (AIE), about which we are thinking during diagnostic process even more in these days. Typical symptoms of AIE are loss of memory, epileptic seizures and psychiatric symptoms. During diagnostic process is important to find positivity of antibodies, in the case of anti-NMDA encephalitis there are antibodies against N-methyl-Daspartate receptors, which are placed on almost all neurons in the brain and spinal cord. Early diagnosis and treatment of this disease is an important prognostic factor. However there are some cases, in which there is no association between anti-NMDA antibodies and autoimunne encephalitis, as we can see in the following case report.

Keywords: anti-NMDA encephalitis, autoimunne encephalitis