Dermatológia pre prax 4/2019
Eruptive dermatofibromas
Dermatofibromas are fibrohistiocytic tumors of the skin with benign potential. They occur most frequently on the lower limbs, typically as the solitary lesions. The eruptive development of numerous dermatofibromas is very rare. An abnormal immune response can be involved in the creation of dermatofibromas. The eruption of multiple lesions can be the first sign of an autoimmune disease or disease associated with immune alteration (such as systemic lupus erythematosus, HIV, sarcoidosis), respectively may indicate insufficient patient management. The authors present a case of a 32-year-old woman with a history of systemic lupus and the formation of numerous hyperpigmented papules on the body with subjective itching, pain and exulceration at the areas of pressure. Histological examination of the lesion confirmed the diagnosis of dermatofibroma. The typical changes of systemic lupus were observed in the sample. The eruption of dermatofibromas stabilized after increasing the dose of antimalarics.
Keywords: eruptive dermatofibromas, dermatofibromas, benign tumors, immunodeficiency, systemic autoimmune disease
