Anestéziológia a intenzívna medicína 2/2023

Metformin-associated lactic acidosis − a case report

The authors describe a case of a 38-year woman who overdosed on metformin with suicidal intent, with the development of severe lactic acidosis and acute renal failure, which required hemodialysis. They are dealing with etiology, patophysiology, treatment and risk factors for developing metformin – associated lactis acidosis. The authors point to importance of multidisciplinary approach to managing and preventing metformin – associated lactic acidosis.

Keywords: metformin, metabolic acidosis, lactate, sodium bicarbonate, hemodialysis, case report